Speakers

The 2019 NW ASM Branch meeting will have presentations from faculty, postdoctoral fellows and graduate students from 7 different institutions in the northwest region as well as a highly anticipated keynote address from Stephen M. Beverley, an ASM distinguished lecturer from the Washington University School of Medicine. 

 

KEYNOTE ADDRESS

Stephen M. Beverley 

Ph.D, Washington University

ASM Distinguished Lecturer

Role of RNA Viruses as Pathogenicity Factors in Protozoan Parasites

Many protozoans contain endogenous viruses; examples include Leishmania, Trichomonas, Giardia, and several apicomplexans including Cryptosporidium, Babesia, and Toxoplasma. Focusing mostly on Leishmania, we showed a few years ago that these actually contribute towards parasite virulence in animal models and probably in humans. As endobiont viruses, these in effect constitute the “virome within.”  Lecture topics would include the emerging parasite viromes including viral discovery, the structure and functional relationships of viruses within the parasite host, how these contribute to mammalian pathogenicity, and exploiting these viruses as therapeutic targets. Leishmania will be the central paradigm but studies of the other protozoal viruses will be incorporated depending on the specific lecture.

Dr. Beverley’s laboratory studies the biology of the protozoan parasite Leishmania, including virulence factors, host response and basic metabolic functions. His laboratory has focused on the development of genetic tools and their applications to diverse questions in Leishmania biology, more recently incorporating genomic and gene editing approaches. Recent foci include the study of the RNAi interference pathway as a tool and also the forces contributing to its loss during evolution in some Leishmania species. These studies have led his laboratory into the study of Leishmania RNA viruses and their role in parasite virulence. Translational interests include the identification of chemotherapeutic targets and live vaccination strategies.

Dr. Beverley earned his Ph.D. in biochemistry from the University of California, Berkeley, and did postdoctoral research at Stanford University. In 1983 he moved to Harvard Medical School and went on to become Professor and Interim Chair of the Department of Biological Chemistry & Molecular Pharmacology. In 1997 he joined the faculty at Washington University School of Medicine in St. Louis as Head of the Department of Molecular Microbiology. He is a Burroughs-Welcome Scholar in Molecular Parasitology, a member of the US National Academy of Sciences, a member of the American Academy of Microbiology, a Fellow of the AAAS, and a Fellow of the American Society of Tropical Medicine and Hygiene. In 2017, Dr. Beverley received the Peter Raven Lifetime Achievement Award from the St. Louis Academy of Sciences.

CRAIG MOYER

Ph.D,  Professor, Western Washington University

“Fine-Scale Biogeography and the Inference of Ecological Interactions among Neutrophilic

Iron-Oxidizing Zetaproteobacteria as Determined by a Rule-Based Microbial Network”

JEAN CELLI

Ph.D, Associate Professor,

Washington State University

"Modulation of Golgi-associated traffic by bacterial effectors"

JAY MELLIES

Ph.D, Professor,

Reed College

"Naturally Occurring Consortia of Bacteria Degrade Common Plastics"

NAEHA SUBRAMANIAN,

Ph.D, Assistant Professor

Institute for Systems Biology

"A host innate immune circuit controls inflammasome activity and immune escape of Salmonella inside macrophages"

JONATHAN PRUNEDA

Ph.D, Assistant Professor, Oregon Health & Science University

"How pathogenic bacteria subvert host ubiquitin signaling"

ISABELLA RAUCH

Ph.D, Assistant Professor

Oregon Health & Science University

"Epithelial NAIP-NLRC4 inflammasome induced cells extrusion defends against gastrointestinal pathogen invasion"

HOLLY PINKART

Ph.D, Professor, Central Washington University

"The utility of fecal microbiome as a proxy for the gut microbiome"

DANA SHAW

Ph.D, Assistant Professor, Washington State University

"Under Pressure: Stress and Immunity at the Pathogen-Vector Interface"

CHRISTY ANDRADE

Ph.D, Assistant Professor, Gonzaga University

"Phage hunting with mosquitoes: the discovery of novel Aeromonas phage"

TAYLOR STEPIEN

Graduate Student, University of Washington

"Mechanisms of Salmonella Typhi Persistence in Human Macrophages"

AMELIA SILVA

Graduate Student, Washington State University

"The Yersinia pestis Csr system coordinates efficient biofilm-mediated blockage of the flea foregut"

BLAIR ARMISTEAD

Graduate Student, University of Washington

"Novel insights into the Group B Streptocuccus hemolytic pigment "

ROCHELLE GLOVER

Graduate Student, University of Washington

"A genome-wide CRISPR-Cas9 knockout screen to identify host determinants of Listeria monocytogenes virulence gene regulation"

SAVANNAH SANCHEZ

Graduate Student, Washington State University

"The ferriphilic nature of Coxiella burnetii during axenic growth suggests a greater role for iron during replication and viability of this obligate intracellular bacterium"

NEEL SALUKHE

Graduate Student, University of Washington

"Establishing the Role of Apobec1-mediated editing during Alphavirus replication"

HANNAH LEDVINA

Graduate Student, University of Washington

"Tn-Seq reveals hidden complexity in the utilization of host-derived glutathione in Francisella tularensis"

KEYA SEN, PhD

Part-Time Lecturer, University of Washington Bothell

Fullbright Global Scholar (2016-2019)

"Isolation of Multi-Drug Resistant E. coli Including ST131, from a Constructed Wetland  Dominated by a Crow Roost"

ADAM BROTHERS

PharmD, Seattle Children's

"Utilizing Clinical Microbiology Data to Facilitate Hands-off Stewardship"

ANN MELVIN

M.D., Professor, Seattle Children's

"The role of the laboratory in the work-up of child sexual abuse"

DEIRDRE RUIZ

Seattle Children's

"Red Flag Fungus"

ANDREW BRYAN 

M.D., Ph.D, Assistant Professor, University of Washington

TBA

CALEB STOKES

M.D., Ph.D, Seattle Children's

"How Zika Virus Hijacks Immune Signaling and Hurts Brain Development"

RAFAEL HERNANDEZ

M.D., Ph.D, Seattle Children's

TBA

AMIN ADDETIA

Seattle Children's

"Genomic insights into sexually transmitted pathogens, new and old"

Questions? Contact: 

Dr. Steve Libby 
2019 Meeting Coordinator

Secretary-Treasurer, Northwest Branch ASM

Dr. Jay Mellies
President, Northwest Branch ASM

NW ASM Connect

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